Week 4 doesn’t just have big games. It has landmines.
With conference play settling in and the Power Four schedules turning mean, several ranked teams are walking into situations that can flip fast. The SEC, in particular, is loaded: a record four AP Top 25 matchups give Saturday a feel that could reshape the early playoff picture before the night is over.
That’s the backdrop for a weekend where favorites need to be sharp from the first snap. Road trips, pressure spots and teams still trying to figure out who they really are are all in play. Here are the six teams worth watching closely for upset danger.
No. 1 Texas heads to No.
14 Tennessee as a 5.5-point favorite, and Arch Manning is about to get his first taste of a hostile road setting in 2026. Manning says he has never been to Knoxville, and that alone makes this one feel different.
If Tennessee gets the first punch in and forces Texas to play from behind, the pressure on the Longhorns offense could spike in a hurry. Josh Heupel’s record against top-25 teams with the Vols is 11-14, but he’s 5-6 at home in those games, with wins over Florida, Alabama and Kentucky in 2022, Texas A&M in 2023 and Alabama in 2024.
Tennessee hasn’t been talked about much as a true SEC threat, but that changes fast if freshman quarterback Faizon Brandon has the kind of breakout game that outshines Manning.
No. 15 Utah also lands in the danger zone, even if the conversation around the Utes has been mostly about how dominant they’ve looked.
Their average margin of victory is 39.3 points per game, and the offense has been pushing toward program highs. Still, the test now is different: Iowa State is the team with a chance to make this ugly on the road.
First-year coach Jimmy Rogers has already given the Cyclones belief, which is half the fight in a transition season. The key for Iowa State is simple enough - make Devon Dampier uncomfortable in his first road start of his senior season.
He hasn’t been pressured much yet, and that’s the opening the Cyclones need.
No. 16 Louisville gets Wake Forest at home as a 12.5-point favorite, but this is the kind of ACC game that can sneak up on a team riding high.
Jeff Brohm has to keep his group locked in after last week’s win over SMU, because emotional carryover can be a problem when the opponent doesn’t look intimidating on paper. The Mustangs were the Cardinals’ last top-25 opponent on the schedule, and with the two toughest games now behind them, Louisville’s CFP hopes have started to climb.
But Wake Forest showed against Miami that it can hang around and make things competitive, and that matters here against a Cardinals team that may not be as explosive across the board as the ACC’s clear frontrunner.
Michigan is in a tricky spot at No. 18, even at home against No. 17 Iowa.
The Wolverines have already shown plenty of volatility: they nearly lost to Western Michigan in the opener, managed just 17 points in a win over Oklahoma, and then shook off a rough start to hammer UTEP after a 28-point third quarter. That’s not exactly the profile of a team that should be comfortable against Iowa.
Bryce Underwood and this offense are going to have to earn every yard against a Hawkeyes defense that has two shutouts and has allowed only one offensive touchdown. Hank Brown has done enough through the air to keep defenses honest, which is why this one feels like it could turn into a grind where 14 points might be enough.
NC State is another team with alarm bells ringing. The Wolfpack host Appalachian State after last week’s stunning finish at Vanderbilt, when quarterback CJ Bailey fumbled in the end zone with one second left and handed the Commodores a go-ahead defensive touchdown.
All he had to do was go to the ground, and NC State might have sealed the win. Instead, the loss added to a rough stretch that also includes the opener at Virginia, and it’s fair to wonder how much more the Wolfpack can absorb under Dave Doeren.
The way that game ended felt like the kind of mistake that can linger. Appalachian State comes in unbeaten after beating Maine, ECU and Charlotte.
UCLA rounds out the list with a cross-country trip to Maryland, and that alone makes this one worth a hard look. The Bruins are 2.5-point favorites, but Maryland is the team under real pressure after falling to Virginia Tech.
For Mike Locksley, this has the feel of a must-win if he wants to keep his tenure in College Park on track. A loss would only deepen the sense that things are slipping, even with a roster that has talent.
The Terrapins still have Nebraska and Ohio State ahead, so this is the spot where they need to capitalize at home as an underdog. UCLA, meanwhile, is coming off a game in which it allowed 425 passing yards against Purdue, which only adds to the uncertainty.
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