The San Francisco 49ers are set to headline one of the nine NFL International Series games in Mexico City during the 2026 regular season. While the exact date and opponent are still under wraps, the 49ers' presence is confirmed, promising an exciting showcase south of the border.
In addition to their Mexico City appearance, the 49ers will embark on a historic journey to Australia, where they'll face off against the Los Angeles Rams in Melbourne. This matchup marks the NFL's inaugural game in Australia, scheduled for the opening week of the regular season on September 9th or 10th.
The 49ers have fond memories of Mexico City, having defeated the Arizona Cardinals there in 2022 and also playing a game back in 2005. Their 2026 travel itinerary is ambitious, with a record-setting 38,000 air miles on the docket, as noted by the San Francisco Chronicle.
As for their international "home" game, the 49ers could potentially face any of their scheduled home opponents: the Eagles, Cardinals, Seahawks, Commanders, Vikings, Raiders, Broncos, or Dolphins. However, it's unlikely the Rams will be their opponents in Mexico City, given their already scheduled clash in Australia.
The full 2026 NFL schedule is slated for a May release, but one thing's for sure: the 49ers' global journey is set to captivate fans worldwide, blending the thrill of football with the allure of international venues.