49ers Get A Huge Availability Swing Before Seahawks Showdown

With Mike Evans cleared to play, the 49ers are gearing up for a challenging face-off against the Seattle Seahawks, as injuries continue to impact their lineup.

The 49ers head into their Week 5 trip to Seattle with one major bit of good news on offense: Mike Evans is clear to go.

After Friday’s practice, Kyle Shanahan wiped away Evans’ injury designation, removing the uncertainty that had followed the wide receiver since he suffered a rib injury two weeks ago. Evans was able to play against Denver in Week 4, but there had still been some lingering doubt about whether he’d be ready to handle another game just days later. That concern is gone now.

San Francisco’s latest injury report also delivered the other side of the story: several key names are out, and the list includes Kyle Juszczyk, who left the Broncos game with a hyperextended knee. Shanahan said Juszczyk figures to miss a couple of weeks, a setback that will force the 49ers to lean on Brock Purdy and the offense to adjust against a Seattle defense that has already given them problems.

The full report from Shanahan listed the following players as unavailable:

Out

FB Kyle Juszczyk (knee)

DE Nick Bosa (calf)

DT James Thompson Jr. (ankle)

DB Marques Sigle (ankle)

San Francisco also had one player listed as questionable:

DB Upton Stout (shoulder)

DE Mykel Williams (knee)

Williams, though, is trending in the right direction. The 49ers are planning to activate him from the physically unable-to-perform list, a move that would bring back the 2025 Round 1 NFL Draft pick after last year’s ACL tear wiped out much of his offseason work and the first four weeks of the season. To make that happen, the team is set to release defensive lineman Ogbo Okoronkwo.

Williams won’t be expected to look fully settled right away, especially after that kind of injury layoff. But with San Francisco’s defensive front already stretched thin for much of the year, getting him back gives the group a much-needed boost.

The 49ers and Seahawks meet Sunday, Oct. 11 at 4:25 p.m. ET from Lumen Field.

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