Oklahoma State heads to Manhattan on Saturday with a chance to bounce back quickly from a wild loss, and the matchup with Kansas State will kick off at noon CT from Bill Snyder Family Stadium.
The Cowboys enter Week 10 at 5-3 overall and 3-2 in Big 12 play after falling 51-49 at Iowa State last Saturday. Kansas State comes in at 4-4 and 1-4 after a 27-24 overtime loss at Colorado.
The game will air on TNT, with streaming available on Fubo, which offers a free trial.
Kansas State is still without starting quarterback Avery Johnson, and Blake Barnett is expected to get the start.
BetMGM listed Oklahoma State as a 7-point favorite Friday, Nov. 6.
The over/under is 62.5, and the moneyline has OSU at -235 and Kansas State at +195. The prediction attached to the matchup: Oklahoma State 42, Kansas State 24.
For the Cowboys, the trip to Manhattan comes with a straightforward test after last week’s defensive collapse. The Wildcats, meanwhile, are likely to turn to their fourth starting quarterback in as many weeks.
Here’s the full Week 10 Big 12 slate, all times CT: Friday, Arizona 29, TCU 28; BYU at Utah, 11 a.m. Saturday on ABC; Iowa State at Baylor, 11 a.m.
Saturday on FS1; Oklahoma State at Kansas State, noon Saturday on TNT; Cincinnati at Houston, 2:30 p.m. Saturday on Fox; UCF at Kansas, 2:45 p.m.
Saturday on ESPN2; Colorado at Arizona State, 6:30 p.m. Saturday on ESPN2; and West Virginia at Texas Tech, 8:30 p.m.
Saturday on ESPN.
Oklahoma State’s 2026 schedule, all times Central, includes: Tulsa 24, OSU 10; OSU 39, Oregon 31; OSU 59, Murray State 0; OSU 41, West Virginia 24; OSU 42, UCF 28; Houston 35, OSU 32; OSU 57, Colorado 24; Iowa State 51, OSU 49; at Kansas State, noon Saturday on TNT; vs. Texas Tech, TBA; at Arizona State, TBA; and vs. Kansas, TBA.
Kansas State’s 2026 schedule, all times Central, includes: Kansas State 71, Nicholls 3; Kansas State 34, Washington State 7; Kansas State 31, Tulane 20; Cincinnati 31, Kansas State 26; Houston 35, Kansas State 16; Kansas State 35, Kansas 24; Arizona State 28, Kansas State 17; Colorado 27, Kansas State 24; vs. Oklahoma State, noon Saturday on TNT; at TCU, TBA; vs. Arizona, TBA; and at Iowa State, TBA.
Entering Saturday’s games, the Big 12 standings are led by Utah, BYU and Texas Tech, with Oklahoma State sitting seventh at 5-3 overall and 3-2 in conference play. Kansas State is tied near the bottom at 4-4 overall and 1-4 in the league.
In Other News...
Oklahoma State's Offensive Outburst Raised One Big Early Question
Oklahoma States season opener turned into a runaway at Gallagher-Iba Arena, where the Cowboys overwhelmed Queens (NC) 118-68 behind a blistering shooting night and a deep bench. Oklahoma State hit 62.0% of its shots, knocked down 16 three-pointers and got 74 points from its reserves, the kind of all-around offensive burst that can make an early November game feel over before it settles in.
The performance also came with a pile of record-book footnotes, a reminder that the Cowboys were not just efficient but disruptive from start to finish. There was plenty to like in the pace, the balance and the pressure, even if the bigger question now is how much of that production can carry over when the competition tightens and the easy baskets disappear. [Read more 🡒]
Oklahoma State Enters Crucial Road Test With A New Defensive Concern
Oklahoma State heads into a tricky road matchup at Kansas State with its defensive depth already getting tested. The Cowboys will be missing linebacker Tate Romney and defensive end Jaleel Johnson, part of a group of five players ruled out for the game, while two others were taken off the injury report and appear set to be available.
The timing matters because this is the kind of Big 12 trip where every available body counts, especially on a defense trying to hold up away from home. Kansas State has its own injury questions after downgrading four players to doubtful and upgrading one to probable, but Oklahoma State still has to sort through a thinner rotation and find answers on the fly before kickoff. [Read more 🡒]
Oklahoma State Finally Delivered The Breakthrough Fans Had Been Waiting For
For a team that had spent too much of the Big 12 season chasing a first-half foothold, Saturday finally brought the kind of start Oklahoma State had been waiting for. The Cowboys jumped on Kansas State early and never let up in a 66-28 win, scoring touchdowns on all four first-quarter drives and taking a 35-point lead into halftime, their first Big 12 halftime advantage of the year. Drew Mestemaker was sharp from the outset, completing all nine of his passes for 117 yards, while Caleb Hawkins kept the pressure on with a bursty ground game that helped turn the afternoon into a runaway.
The bigger picture was just as important as the scoreboard. With the victory, Oklahoma State became bowl eligible for the first time since 2023, a needed milestone for a program looking to steady itself after a rocky stretch. The defense also had its own breakout moments, with sophomore cornerback LaDainian Fields coming up with two interceptions as the Cowboys put together a complete performance that felt overdue in every phase. [Read more 🡒]