Week 4 is lined up to test a handful of ranked teams that are already walking a tightrope.
The biggest pressure point sits in Knoxville, where No. 1 Texas brings its unbeaten record into a road game against Tennessee on Saturday night.
The Longhorns are coming off a 30-6 win over UTSA, but that result did little to quiet concerns after a sluggish follow-up to their thriller against Ohio State. Arch Manning finished that game 16/32 for 161 yards, and Texas needed second-half work to pull away.
On the road for the first time outside Austin, that kind of start won’t be enough.
Tennessee has opened 3-0 and handled each of its first three opponents. Freshman quarterback Faizon Brandon, a former five-star recruit, has been ahead of schedule so far.
He has completed 64.1% of his passes for 552 yards with 6 touchdowns and 0 interceptions, while adding 137 rushing yards and 3 more scores. If Brandon gets rolling early, Texas could be in for a long night.
Manning, meanwhile, has been inconsistent enough that the Longhorns can’t count on a late surge to save them every week. Texas needs to start fast and take the crowd out of the game.
Florida’s matchup with Ole Miss carries a different kind of tension. The Gators are technically favored, but the Rebels come in with the better ranking and have already knocked off two ranked opponents.
Their latest statement came in a 32-24 win over top-10 LSU, a result that only sharpened the oddsmaking debate. Jon Sumrall even questioned what Vegas was thinking.
There’s also real shootout potential in Gainesville. Florida has one of the country’s most dangerous rushing attacks, averaging 246 yards per game on the ground behind Jadan Baugh.
Ole Miss has its own firepower, with Trinidad Chambliss looking even better than he did a year ago and carrying Heisman buzz. The one major name to monitor is Kewan Lacy, who is considered doubtful.
That would be a significant loss for the Rebels if he can’t go.
USC is another team that has been living dangerously. The Trojans barely escaped Rutgers, winning 42-35 in a road game that stayed tight for most of the second half.
Jayden Maiava has been electric and is leading the country in passing yards and passing touchdowns, but the defense keeps leaving the door open. USC has allowed 26 or more points in three of four games, including back-to-back outings of 30-plus against Louisiana and Rutgers.
Keep playing with that kind of margin, and eventually it catches up.
Missouri also enters Week 4 with questions hanging over it, even if the matchup on paper looks manageable. Mississippi State has already matched its win total from 2025 and has won back-to-back road games at Minnesota and South Carolina.
Bulldogs sophomore quarterback Kamario Taylor is becoming a name to know, with 56 completions on 82 attempts for 832 yards, 11 touchdowns and 1 interception, plus 178 rushing yards and another score. Jeff Lebby has the program in a good place.
Missouri hasn’t looked sharp in its wins over Kansas and Troy. Against Troy, the Tigers scored 24 of their 27 points in the second quarter, then went quiet until the final frame.
The Trojans even led 10-0 at one point. If Missouri doesn’t put together a full four quarters, Mississippi State has enough momentum to make this one uncomfortable.
West Virginia, meanwhile, is trying to push itself into the top 25 for the first time since 2018. The Mountaineers earned that kind of attention with a 38-27 upset of ranked Virginia in Charlotte, holding the Cavaliers to 13 points over the final three quarters. Now the schedule shifts to Big 12 play, starting with Oklahoma State.
That game has its own upset feel after the Cowboys knocked off No. 6 Oregon 39-31 two weeks ago, then followed it with a 59-0 win over Murray State.
The season-opening loss to Tulsa suddenly looks far behind them. West Virginia will lean on quarterback Michael Hawkins Jr. and his dual-threat ability, but Oklahoma State has already shown it can land a punch.
Drew Mestemaker, who likes being the underdog, could be the one to do it again.
In Other News...
Mizzou Faces An Early SEC Test Fans Already Fear Could Expose Them
Week 4 brings an early measuring-stick Saturday for Missouri, with the Tigers headed to Mississippi State in one of four ranked SEC matchups on a slate that will start sorting contenders from pretenders. The full board also includes Texas at Tennessee, giving the conference a loaded day of high-profile games that should say plenty about where the league hierarchy is headed, even if September still leaves room for plenty of movement.
For Missouri, the trip is less about headlines than it is about proof, because a road game like this tends to reveal whether a teams strengths travel and whether the pressure of SEC play changes the picture. The matchup has already drawn expert predictions and betting angles, but the real tension is simple enough: can the Tigers handle an opponent that gives them an honest test, or will this be the kind of game that leaves fans wondering what the ceiling actually is? [Read more 🡒]
Texas Faces A Backfield Concern Right Before Week 4
Injury updates around the SEC already shaped up to be part of the Week 4 conversation on College GameDay, with ESPNs Pete Thamel laying out the status of several backs in the conference. Texas is expected to have Hollywood Smothers dress and try to go through an ankle injury, Ole Miss is bracing for the likely absence of Kewan Lacy because of a shoulder issue, and Floridas Eric Singleton Jr. is still headed toward a game-time call after his own ankle problem.
For Missouri, the attention turns to Ahmad Hardy, who has not practiced yet after surgery, leaving the Tigers to wait on a key piece as they move through the week. The timing matters because Missouri has already ruled him out for Saturdays game at Mississippi State, and the next step is about more than just pain tolerance, it is about whether he can get back on the field with enough ramp-up to be ready when the Tigers need him again. [Read more 🡒]
Mizzou Heads Into Another SEC Test With A New Lineup Problem
Missouri is heading into another SEC test with more shuffling to do on both sides of the ball. Defensive end Darris Smith was ruled out on the league availability and injury report for the game against Mississippi State, while star running back Ahmad Hardy and backup Malae Fonoti also showed up as out for the Tigers. It is the latest reminder that depth has become part of the week-to-week conversation as Missouri tries to keep its footing in conference play.
Smiths absence is especially notable because he had already been a key piece on the edge before getting hurt against Troy, and Missouri has to account for that loss while trying to steady a defense facing another physical opponent. Hardys status adds a different kind of pressure on the offense, since the Tigers are still waiting on his return timeline, and the backfield picture remains unsettled as Missouri looks for answers going into Saturday. [Read more 🡒]