Missouri Faces Miami: Can the Tigers Pull Off a March Madness Stunner?

Expertly navigating potential upsets and standout performances, the Tribune unveils its bold predictions for a thrilling 2026 NCAA men's tournament.

March Madness Predictions: Upsets, Sweet 16 Hopefuls, and a Champion in the Making

As the First Four wraps up, the madness of March is in full swing, and we're ready to dive into the heart of the tournament. While some may argue for expansion, let's focus on the excitement at hand. Texas fans, you might still be scratching your heads after those last two minutes against NC State, but that's the unpredictability we love.

Missouri's Big Test

Missouri basketball fans, mark your calendars for 9:10 CDT on Friday. The 10-seeded Tigers are set to face a formidable 7-seed in Miami.

It's practically a home game in St. Louis, but don't let that fool you-Dennis Gates and his squad are in for a tough battle against Jai Lucas’ stylistically similar Hurricanes.

First-Round Upset Alerts

Let's get to the juicy part: our favorite first-round upset picks. We're backing three of the four 9-seeds to advance.

Iowa, under Ben McCollum, is poised to take down 8-seed Clemson. TCU looks ready to topple 8-seed Ohio State, and Utah State seems undervalued as a 9-seed against Villanova.

Sorry, SLU fans, but we see Georgia coming out on top in that matchup.

The biggest upset on our radar? 13-seed Hofstra over 4-seed Alabama. With distractions swirling around Alabama, Hofstra might just capitalize on the chaos.

On the flip side, don't be swayed by the buzz around 13-seed Cal Baptist over 4-seed Kansas or 12-seed Northern Iowa over 5-seed St. John’s. These trendy picks aren't likely to pan out.

However, keep an eye on 11-seed USF against 6-seed Louisville, especially with the Cardinals missing their star freshman, Mikel Brown.

Predicting the Sweet 16

When it comes to 1-, 2-, and 3-seeds, expect them to power through to the second round. The divide between the top teams and the rest is wider than ever. But if you're looking for a potential upset, Purdue might face a challenge from either Missouri or Miami.

UCLA as a 7-seed could pose a threat to 2-seed UConn, though we're not betting on it. And while Duke should handle TCU/Ohio State, injuries could make it closer than expected.

In the SEC, we're picking three teams to make it to the second weekend: Florida, Arkansas, and Vanderbilt.

Final Four Forecast

Could we see another year of top seeds dominating? It's possible.

Arizona and Michigan are our top picks to make the Final Four. The South Region, though, is a minefield.

Florida's recent form is promising, but Illinois and Houston are lurking. We're backing the Cougars to break through.

Duke's injury woes might catch up with them, but with Cameron Boozer leading the charge, they're still a strong contender. Kansas, St. John’s, UConn, and Michigan State all have the coaching pedigree to challenge the Blue Devils.

And the Champion Is...

Despite the injury setbacks, Duke has been a powerhouse. But if Michigan squares off against Arizona in the Final Four, expect fireworks.

We're putting our chips on Michigan to take home the national title. With their world-beating performances and Dusty May at the helm, the Wolverines have what it takes to cut down the nets.

Get ready for a wild ride, basketball fans. March Madness is here, and it's going to be unforgettable.