The Colts are back at Lucas Oil Stadium on Sunday, and Week 6 brings a divisional matchup with the Tennessee Titans.
Indianapolis enters at 2-3 after last week’s disappointing loss in Pittsburgh, while Tennessee comes in at 0-5. The Colts will be looking to turn that trip home into a much-needed win.
The game will air on FOX, with kickoff set for 1:00 PM ET on Sunday, Oct. 18. Fans can also stream the matchup on FUBO.
Chris Myers, Jonathan Vilma, and Jen Hale will be on the call for the game.
Pete Prisco of CBS Sports is picking the Colts to win comfortably, projecting a 28-17 Indianapolis victory. “The winless Titans head out on the road to play a Colts team that has been inconsistent.
The Colts' defense has improved in recent weeks, which will challenge Cam Ward and the Titans' limited offense. Look for the Colts to get a division victory as Jonathan Taylor has a big game.”
Here’s a look at the Colts’ 2026 regular season schedule:
Week 1: vs. Baltimore, 1:00 PM, CBS
Week 2: at Kansas City, 8:20 PM, NBC (SNF)
Week 3: vs.
Houston, 1:00 PM, CBS
Week 4: at Washington (London), 9:30 AM, NFLN
Week 5: at Pittsburgh, 1:00 PM, CBS
Week 6: vs.
Tennessee, 1:00 PM, FOX
Week 7: at Minnesota, 1:00 PM, CBS
Week 8: at Jacksonville, 1:00 PM, CBS
Week 9: vs.
Dallas, 1:00 PM, FOX
Week 10: vs.
Miami, 1:00 PM, CBS
Week 11: at Houston, 8:15 PM, AMZ (TNF)
Week 12: vs. New York Giants, 1:00 PM, FOX
Week 13: BYE
Week 14: at Philadelphia, 1:00 PM, FOX
Week 15: at Tennessee, 1:00 PM, CBS
Week 16: vs.
Cincinnati, TBD
Week 17: at Cleveland, 1:00 PM, FOX
Week 18: vs. Jacksonville, TBD
In Other News...
Colts Suddenly Have A Tyler Warren Concern Before Week 6
The Colts entered the weekend with a familiar kind of late-week uncertainty, and it landed on one of their most important young playmakers. Tyler Warren was added to the injury report Friday after getting hurt in practice, turning what had been a normal build toward Week 6 into a sudden concern for Indianapolis as it prepares for the next step in its schedule.
Warren is listed as questionable, which leaves the Colts waiting to see how much they can count on the tight end before kickoff. For a team trying to keep momentum, any late addition to the report is worth watching, especially when it involves a player who has quickly become a central part of the offense. [Read more 🡒]
Colts' Defensive Overhaul Is Creating A Problem Fans Feared
Chris Ballard spent the offseason trying to remake the Colts defense into something younger and faster, but the first month-plus of the season has brought an uncomfortable tradeoff. Through five games, Indianapolis has not gotten the payoff it was chasing, and the run defense has been a particular problem as opponents have found more room on the ground than they did a year ago.
Some of that comes with the territory when a roster leans harder on developing players, and the Colts are still sorting out how the new pieces fit together in real games. The concern for fans is less about the concept of the overhaul and more about whether the current personnel is sturdy enough to hold up against the run while the younger players continue to grow into larger roles. [Read more 🡒]
Jonathan Taylor Faces A Frustrating Test Colts Fans Can't Ignore
Jonathan Taylors start has been quieter than Colts fans are used to, with the running back averaging 3.9 yards per carry and ranking 23rd in breakaway rate, according to PFF. The bigger concern is how that production has fit into an offense still searching for rhythm through the air, because when the passing game is sputtering, defenses can focus more attention on Taylor and make every carry feel harder than it should.
The next test comes against Tennessee, and it shapes up as a tough measuring stick for the ground game. The Titans have been stingy against the run this season, allowing just 3.5 yards per rush, and the matchup puts even more pressure on Indianapolis to find cleaner lanes and better balance if it wants Taylor to get back on track. [Read more 🡒]