Ten ACC teams still enter the weekend without a conference loss on their record, but the league starts to sort itself out fast once Clemson and Cal kick things off Friday night.
That matchup lands as one of four ACC games featuring teams with unblemished league marks, though three of those clubs won’t even play their first conference game until Saturday. Cal and Clemson both sit at 1-0 in ACC play, and the Bears have a chance to keep climbing.
A win would move Cal into a tie for first with No. 6 Miami, and possibly Louisville as well.
A loss for Stanford later in the weekend would leave the Cardinal alone at the bottom of the standings.
Cal’s case is built on something the program has not done in a long time. The Bears have not finished with a winning conference record since 2009, and they have not opened league play 2-0 since Jared Goff’s final season in 2015.
They can do it here. Cal also owns the only previous meeting between the teams, a 37-13 rout of Clemson in the Florida Citrus Bowl on Jan.
1, 1992. After becoming the first Cal back to go over 100 yards against Clemson, Russell White said, “I’m used to raining on people’s parades.”
Saturday brings a full slate of ACC games that should help clear the picture a bit more.
Wake Forest, listed at plus-13.5, heads to No. 16 Louisville for a 9 a.m. kickoff on ESPN.
The two teams are giving up the same number of points - 28.3 per game, tied for 14th in the ACC - but Louisville has separated itself on offense. The Cardinals rank third in the conference at 46.0 points per game, while Wake is 14 points behind.
The Demon Deacons may also be without quarterback Gio Lopez, who is listed as questionable.
Virginia Tech travels to Boston College for another 9 a.m. start, with both teams opening conference play. The 3-0 Hokies are one of four unbeaten ACC teams, and Ethan Grunkemeyer has been sharp for them, averaging 282 passing yards while throwing 101 passes without an interception. Boston College’s Mason McKenzie has been productive in a different way, piling up 648 passing yards and 225 rushing yards.
Florida State, still trying to settle things down on defense, hosts Central Arkansas at noon on ACC Network. The Seminoles are 16th in the ACC in scoring defense after giving up 50 points to Alabama, and this matchup looks far more manageable.
Duke gets William & Mary at 12:30 p.m. on ACC-X. The Tribe has scored at least 20 points in 13 straight games, its longest such run since 2009, but Duke has been stingy, allowing just 12.3 points per game.
Virginia is back home at 3 p.m. on ACC Network after dropping out of the AP Top 25 with a 38-27 loss to West Virginia. Delaware comes in as the opponent, and the Fightin’ Blue Hens are 9-7 in their second season as an FBS program.
No. 6 Miami takes on Central Michigan at 3:30 p.m. on CW Network, and Darian Mensah’s numbers keep jumping off the page.
He is completing 89.9 percent of his passes, with 11 touchdown throws and only eight incompletions. Central Michigan’s three quarterbacks, by comparison, have combined to complete 47.7 percent of their attempts with three interceptions and no touchdowns.
North Carolina State hosts Appalachian State at 4:30 p.m. on ESPNU, and Wolfpack quarterback CJ Bailey is looking for a clean game after last week’s nightmare finish. He fumbled in the end zone while trying to run out the clock, and Vanderbilt recovered for a 35-31 win.
SMU is back at home at 6 p.m. on ACC Network after a 10-point loss at Louisville. The Mustangs, who average 38 points, meet Missouri State, which opened the season with a 50-0 loss to Texas A&M.
The night closes with Georgia Tech at Stanford at 7:30 p.m. on ESPN. Stanford has been outscored 80-13 and outgained 1,019 yards to 536 in two ACC losses, and now it draws quarterback Alberto Mendoza, younger brother of 2026 No. 1 draft pick Fernando Mendoza, who led Cal to wins in the 2023 and ’24 Big Games.
Game odds refresh periodically and are subject to change.
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