Buffalo Bills Eye Key Prospects at 2026 NFL Combine
As the NFL Combine festivities kick off in Indianapolis, the Buffalo Bills are set to evaluate the upcoming draft class, focusing on bolstering their roster in crucial areas. With General Manager Brandon Beane and Head Coach Joe Brady at the helm, the team is zeroing in on wide receiver, interior offensive line, and defensive positions, especially with the new 3-4 scheme under Defensive Coordinator Jim Leonhard.
Here’s a look at six prospects who could pique the Bills’ interest:
Washington WR Denzel Boston
Denzel Boston from Washington stands out among the first-round-caliber receivers who might be available when the Bills pick at No. 26.
With a strong physical presence, Boston has the potential to be a reliable target. However, his athleticism and ability to separate from defenders have been questioned.
The Bills will be keen to see how Boston performs in agility drills at the Combine, as they seek a game-changer on the outside.
Missouri OG Keagen Trost
With potential changes looming on the offensive line, Missouri’s Keagen Trost could be a valuable addition. Likely a Day 3 pick, Trost offers depth and versatility, having played right tackle in the SEC after transferring from Indiana State.
At 6-foot-4, 315 pounds, he’s considered undersized but has proven his strength as a run blocker. A solid Combine showing could make him a late-round target for Buffalo.
Miami EDGE Akheem Mesidor
In a draft rich with edge rushers, Miami’s Akheem Mesidor presents an intriguing option for the Bills. At 6-foot-3, 280 pounds, his athleticism is a standout feature.
While not the top pass-rusher from Miami’s roster, his potential fit for Buffalo’s first-round pick is notable. The Bills will be watching closely to see if Mesidor’s Combine performance elevates his draft stock.
Iowa State IDL Domonique Orange
Domonique Orange from Iowa State may not be known for pass-rushing prowess, but his skills as a run defender make him a valuable prospect for the Bills’ new defensive scheme. As a leader at Iowa State, Orange’s ability to penetrate gaps would fit well in Leonhard’s three-man front. While his stock might not see a significant boost from the Combine, his role as a run-stuffer is worth monitoring.
Texas Tech ILB Jacob Rodriguez
Drawing comparisons to Matt Milano, Jacob Rodriguez from Texas Tech is a playmaker with leadership qualities. Though slightly undersized, his effectiveness on defense is undeniable. The Bills are searching for a future leader in the middle of their defense, and Rodriguez’s performance at the Combine could solidify his status as a second-round consideration.
Toledo S Emmanuel McNeil-Warren
Safety prospects like Emmanuel McNeil-Warren from Toledo don’t come around often. Known for his intermediate coverage skills, he’s already been linked to the Bills in mock drafts.
While not the most urgent need, his presence could enhance Buffalo’s secondary. His 40-yard dash performance at the Combine will be crucial in determining his draft position.
As the Combine unfolds, the Bills will be closely evaluating these prospects, looking for players who can make an immediate impact and contribute to their long-term success.