The Buffalo Bills are walking into a brutal stretch of their schedule, but one of the biggest early tests just got a lot less dangerous. As they prepare to face the Houston Texans today, Buffalo is staring down a five-week run that includes four playoff teams from last season in September and early October. One of those matchups is the Los Angeles Rams, and that game has now taken a major turn.
The Rams were supposed to be rolling into the season with a headline-making edge after trading for Myles Garrett from the Cleveland Browns. Garrett, coming off a season in which he set the new sack record, was supposed to give Los Angeles a true game-wrecker and push them into the Super Bowl favorite conversation.
Instead, his debut week went sideways. In Thursday’s game in Australia, the Rams were expected to handle a banged-up 49ers team, but San Francisco delivered the blowout instead. Garrett, meanwhile, was a non-factor and didn’t record a single stat, which is about as strange as it gets for a player of his caliber.
Now the reason appears to be much bigger than just an off night. Tom Pelissero reported that Garrett will have arthroscopic surgery on his knee and is headed to injured reserve, which will keep him out for the next four games.
That puts him on the shelf for Buffalo’s Week 5 trip to Los Angeles.
Rams star Myles Garrett will undergo arthroscopic surgery on his ailing knee and is headed to injured reserve, sources tell @ringer @netflixsports.
Garrett has been dealing with lower-leg pain and wasn’t himself in Thursday’s opener. The hope is he’s back in four weeks. pic.twitter.com/naTKJDV06R
- Tom Pelissero (@TomPelissero) September 13, 2026
For Buffalo, that’s a significant break. The Bills still have to navigate a tough early schedule, and if you want to be the best, you have to beat the best. The Rams were supposed to look like one of the league’s top teams, even if one ugly game shouldn’t erase what Sean McVay has built.
But without Garrett, Los Angeles loses the kind of edge that changes game plans. He’s the sort of player who can wreck a drive on his own. The Rams do still have Byron Young, Kobie Turner, and Poona Ford, and Aaron Donald is eventually expected back after agreeing to come out of retirement for this season.
Still, Garrett being out in Week 5 immediately eases the pressure on Buffalo’s offense, especially on tackles Dion Dawkins and Spencer Brown. The Rams can still bring heat, and they may well have Donald by then, but not having Garrett on the field gives the Bills a major reprieve.
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