The Arizona Cardinals get their home opener in Week 2, and the matchup comes with a real test: the defending Super Bowl champion Seattle Seahawks, who have won nine straight meetings against Arizona.
Fresh off a 26-14 win over the Los Angeles Chargers to open the season, the Cardinals have a chance to move to 2-0 after plenty of people didn’t expect them to win two games all year. Now they’ll try to knock off the champs and make an early statement at State Farm Stadium.
The game will air on FOX. It’s one of the network’s three late afternoon windows, with Chris Myers and Mark Schlereth on the call and Megan Olivi reporting from the sideline. Streaming is available on Fubo, which offers a free trial.
Kickoff is set for 4:25 p.m. ET, which is 1:25 p.m.
Arizona time. Teams will release inactive lists 90 minutes before kickoff.
Arizona’s Week 2 matchup is part of a schedule that now includes the following:
Week 1, Sunday, Sept. 13: Cardinals 26, Chargers 14
Week 2, Sunday, Sept. 20: Home, Seattle Seahawks, 4:25 p.m.
ET
Week 3, Sunday, Sept.
27: Away, San Francisco 49ers, 4:05 p.m. ET
Week 4, Sunday, Oct. 4: Away, New York Giants, 1 p.m.
ET
Week 5, Sunday, Oct.
11: Home, Detroit Lions, 4:25 p.m. ET
Week 6, Sunday, Oct. 18: Away, Los Angeles Rams, 4:05 p.m.
ET
Week 7, Sunday, Oct.
25: Home, Denver Broncos, 4:05 p.m. ET
Week 8, Sunday, Nov. 1: Away, Dallas Cowboys, 1 p.m.
ET
Week 9, Sunday, Nov.
8: Away, Seattle Seahawks, 4:25 p.m. ET
Week 10, Sunday, Nov. 15: Home, Los Angeles Rams, 4:05 p.m.
ET
Week 11, Sunday, Nov.
22: Away, Kansas City Chiefs, 1 p.m. ET
Week 12, Sunday, Nov. 29: Home, Washington Commanders, 4:25 p.m.
ET
Week 13, Sunday, Dec.
6: Home, Philadelphia Eagles, 4:05 p.m. ET
Week 14: BYE
Week 15, Sunday, Dec.
20: Home, New York Jets, 4:05 p.m. ET
Week 16, Sunday, Dec. 27: Away, New Orleans Saints, 1 p.m.
ET
Week 17, Sunday, Jan.
3: Home, Las Vegas Raiders, 4:05 p.m. ET
Week 18, Saturday or Sunday, Jan. 9 or 10: Home, San Francisco 49ers, TBD
In Other News...
Cardinals Home Opener Suddenly Hinges On A Growing Injury Problem
The Cardinals went into the week hoping to settle into a cleaner picture for their first home game, but the final injury report left plenty unresolved. Slot cornerback Garrett Williams will miss a second straight game, and Arizona has six more players listed as questionable heading into the Week 2 matchup with Seattle, including starting guards Isaiah Adams and Isaac Seumalo along with nose tackles Roy Lopez and Andrew Billings.
That kind of uncertainty matters even more in a home opener, when the margin for a fast start can be thin and continuity up front is everything. Seattle brought its own questions into the game, with quarterback Sam Darnold ruled out and several other players still in question, so a lot of the focus now shifts from the matchup itself to who actually makes it onto the field when the Cardinals kick off in front of their home crowd. [Read more 🡒]
Mack Wilson Sr. Gives Cardinals Defense A Different Feel For Seattle
Mack Wilson Sr. is expected to be part of a Cardinals defense that looks a little different heading into another meeting with Seattle, especially after the group put together a strong showing in the win over the Chargers. Wilson was not available when Arizona lost to the Seahawks last season, and his presence this time gives the defense another layer as it tries to carry over the energy from that performance into an important NFC West matchup.
Seattle comes in with some recent offensive issues, which puts even more on Arizonas defense to keep the pressure on and make the most of its current momentum. For the Cardinals, the challenge is less about rediscovering what worked against Los Angeles and more about proving it can travel into a division game where the details tend to matter just as much as the game plan. [Read more 🡒]
Cardinals Fans Will Notice One Big Change At State Farm Stadium
State Farm Stadium is getting a fresh gameday menu for the 2026 season, and Cardinals fans will have plenty to chew on before kickoff. Executive Chef Sean Kavanaugh and Craft Culinary Concepts are rolling out a new lineup of items for the teams nine home games, with dishes spread across specific sections of the stadium so the changes should be hard to miss.
The menu leans into variety, from the Beef Birria Machete quesadilla and BBQ Brisket Burger to a Sonoran Style Seattle Dog, along with gluten-free, vegan and vegetarian options. For a fan base that spends a lot of time thinking about what happens on the field, this is the kind of off-field upgrade that can shape the whole game-day experience, even if the bigger rollout still leaves room for more to come. [Read more 🡒]